Hemoglobin does not bind with:
Correct Answer: HCN
Description: Hemoglobin Combines Reversibly With Oxygen.
Carbon monoxide (CO) combines with hemoglobin at the same point on the hemoglobin molecule as does O2 ; it can therefore displace O2 from the hemoglobin.
CO2 reacts directly with amine radicals of the hemoglobin molecule to form the compound carbaminohemoglobin (CO2 Hgb).
This combination of CO2 and hemoglobin is a reversible reaction that occurs with a loose bond, so the CO2 is easily released into the alveoli, where the PCO2 is lower than in the pulmonary capillaries.
Reference: : Guyton physiology pg no 532,535
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