In a case of acute hemahrosis in hemophilia, treatment with factor VIII along with fresh frozen plasma is given for duration:
**Core Concept**
In hemophilia A, the deficiency of factor VIII leads to spontaneous bleeding into joints (hemarthrosis) due to the inability to form a stable fibrin clot. Treatment involves replacing the deficient factor VIII to restore hemostasis.
**Why the Correct Answer is Right**
The use of factor VIII concentrates is the standard treatment for hemophilia A. Fresh frozen plasma (FFP) is not a preferred choice for treating factor VIII deficiency because it contains only small amounts of factor VIII and may also contain inhibitors. The correct duration of treatment is typically until the bleeding is controlled, usually 7-10 days. This is because the half-life of factor VIII is approximately 8-12 hours, requiring repeated administration to maintain adequate levels.
**Why Each Wrong Option is Incorrect**
**Option A:** This is incorrect because FFP is not a preferred choice for treating factor VIII deficiency.
**Option B:** This is incorrect because the duration of treatment is typically shorter than 2 weeks.
**Option C:** This is incorrect because the treatment duration may vary depending on the severity of bleeding and individual patient response.
**Clinical Pearl / High-Yield Fact**
In hemophilia A, the use of factor VIII concentrates is preferred over FFP due to its higher concentration and lower risk of inhibitor formation.
**Correct Answer: B. 7-10 days**