HBV replication is indicated by –
Correct Answer: HBeAg
Description: Hepatitis B e antigen Hepatitis B e antigen (HBeAg) is an indicator of viral replication. In acute hepatitis B it may appear only transiently at the outset of the illness; its appearance is followed by the production of antibody (anti-HBe). The HBeAg reflects active replication of the virus in the liver. Chronic HBV infection (see below) is marked by the presence of HBsAg and anti-HBc (IgG) in the blood. Usually, HBeAg or anti-HBe is also present; HBeAg indicates continued active replication of the virus in the liver. The absence of HBeAg usually implies low viral replication; the exception is HBeAg-negative chronic hepatitis B (also called 'pre-core mutant' infection, ), in which high levels of viral replication, serum HBV-DNA and hepatic necroinflammation are seen, despite negative HBeAg. Ref Davidson edition23rd pg 875
Category:
Medicine
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now