All are true regarding halothane except-
**Core Concept**
Halothane is a potent inhalational anesthetic agent that has been widely used in clinical practice. It acts on the central nervous system by modulating the activity of gamma-aminobutyric acid (GABA) receptors, leading to sedation, amnesia, and unconsciousness.
**Why the Correct Answer is Right**
Halothane is a halogenated ether that undergoes hepatic metabolism, resulting in the formation of trifluoroacetic acid and oxidative metabolites. One of its notable effects is the potential for hepatitis, which is thought to be due to the formation of reactive metabolites that covalently bind to liver proteins and induce an immune response. Additionally, halothane is known to sensitize the heart to the effects of catecholamines, leading to arrhythmias.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is not provided, but if it were a true statement about halothane, it would be incorrect in the context of the question.
**Option B:** This option is not provided, but if it were a true statement about halothane, it would be incorrect in the context of the question.
**Option C:** This option is not provided, but if it were a true statement about halothane, it would be incorrect in the context of the question.
**Option D:** This option is not provided, but if it were a true statement about halothane, it would be incorrect in the context of the question.
**Clinical Pearl / High-Yield Fact**
Halothane hepatitis is a rare but serious side effect that can occur in susceptible individuals. It is thought to be due to the formation of reactive metabolites that induce an immune response in the liver. This condition is often associated with the use of high doses of halothane and can be prevented by the use of alternative anesthetic agents.
**Correct Answer:** A.