**Core Concept**
The formation of hemoglobin involves the coordination of several proteins and non-protein molecules. Hemoglobin is a tetrameric protein composed of two alpha-globin and two beta-globin chains, which are encoded by distinct genes. The structure of hemoglobin is crucial for its function, including oxygen binding and transport.

**Why the Correct Answer is Right**
The correct answer is **Histidine**. Histidine is a key amino acid involved in the formation of the heme group, which is a critical component of hemoglobin. The heme group contains a porphyrin ring, which is covalently bound to a histidine residue from each of the globin chains. This histidine residue is essential for the binding of oxygen to hemoglobin. The histidine side chain donates a proton to the oxygen molecule, facilitating the formation of a stable oxyhemoglobin complex.

**Why Each Wrong Option is Incorrect**
* **Option A:** Glycine is a small amino acid that is present in the globin chains, but it is not directly involved in the formation of the heme group.
* **Option B:** Tyrosine is an amino acid that is not directly involved in the formation of the heme group or the structure of hemoglobin.
* **Option D:** No option is provided, this option is not available.

**Clinical Pearl / High-Yield Fact**
It's worth noting that mutations in the genes encoding the globin chains, such as beta-thalassemia, can lead to abnormal hemoglobin structures and function. These mutations can result in a range of clinical manifestations, from mild anemia to severe hemolytic disease.

**Correct Answer:** C. Histidine.