**Core Concept**
The question tests the student's knowledge of **histamine receptors** and their antagonists, specifically **H1 receptor blockers**. H1 receptor blockers are used to treat allergic reactions, and some have sedative side effects due to their ability to cross the **blood-brain barrier**.
**Why the Correct Answer is Right**
The correct answer is likely a **second-generation H1 receptor blocker**, which is known for having less sedative action compared to **first-generation H1 receptor blockers**. This is because second-generation H1 blockers are less lipophilic and therefore less able to cross the **blood-brain barrier**, reducing their sedative effects.
**Why Each Wrong Option is Incorrect**
**Option A:** Likely a first-generation H1 blocker with significant sedative effects.
**Option B:** May be another first-generation H1 blocker with sedative properties.
**Option C:** Could be a first-generation H1 blocker known for its sedative action.
**Clinical Pearl / High-Yield Fact**
Students should remember that **second-generation H1 blockers** like **loratadine** or **cetirizine** have fewer sedative side effects, making them preferable for daytime use.
**Correct Answer:** D. Loratadine
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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