A lady in the second trimester underwent a hemogram and her hemoglobin was found to be 6mg%. The gynaecologist suggested for IV transfusion of packed red cells to improve the level. How much of iron is absorbed by transfusion of 2 units of packed red cells?
## **Core Concept**
The question revolves around the concept of iron supplementation through blood transfusions, specifically packed red blood cells (PRBCs), in a pregnant woman with severe anemia. Understanding the amount of iron absorbed from transfused red blood cells is crucial for managing iron deficiency anemia.
## **Why the Correct Answer is Right**
Each unit of packed red blood cells contains approximately 250-300 mg of iron because the average red blood cell has about 1 mg of iron. When 2 units of packed red blood cells are transfused, the total iron content transfused would be roughly 500-600 mg. However, not all of this iron becomes immediately bioavailable. The body can absorb nearly all of the iron from transfused red blood cells over time. Therefore, transfusing 2 units of packed red blood cells can provide approximately **240-280 mg** of absorbable iron, considering an average absorption rate.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option suggests a much lower amount of iron than what is expected from 2 units of PRBCs.
- **Option B:** While closer, this still underestimates the amount of iron provided by 2 units of packed red cells.
- **Option D:** This option overestimates the amount of iron absorbed from 2 units of packed red blood cells.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that while oral iron supplements are the first line for iron deficiency anemia, in cases of severe anemia or when rapid correction is needed (like in pregnancy), IV iron or blood transfusions may be considered. Each unit of packed red cells provides about 250-300 mg of iron, making blood transfusions an efficient way to replenish iron stores.
## **Correct Answer:** C.