Small vessel vasculitis are -a) Classical PANb) Wegner’s granulomatosisc) Giant cell arteritis d) HSPe) Churg-strauss syndrome
**Core Concept**
Small vessel vasculitis refers to a group of disorders characterized by inflammation of the small blood vessels, including capillaries, venules, and arterioles. This condition is often associated with **autoimmune disorders** and can affect various organs. The underlying principle being tested is the ability to distinguish between different types of vasculitis based on the size of the affected vessels and the associated clinical conditions.
**Why the Correct Answer is Right**
The correct answer includes conditions that are known to affect small vessels, such as **Wegener's granulomatosis**, **Churg-Strauss syndrome**, and **HSP (Henoch-Schönlein purpura)**. These conditions are characterized by the presence of **antineutrophil cytoplasmic antibodies (ANCA)** and inflammation of the small vessels, leading to damage of the affected organs.
**Why Each Wrong Option is Incorrect**
**Option A:** Classical PAN (Polyarteritis Nodosa) is a type of medium vessel vasculitis, not small vessel vasculitis.
**Option C:** Giant cell arteritis is a type of large vessel vasculitis, typically affecting the temporal artery and other large arteries.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that small vessel vasculitis often presents with **renal involvement** and **pulmonary symptoms**, and the presence of ANCA can aid in the diagnosis.
**Correct Answer:** D. Wegener's granulomatosis, HSP, Churg-strauss syndrome.