Granular cell myoblastoma of tongue is
**Core Concept**
Granular cell myoblastoma, also known as granular cell tumor, is a rare, benign neoplasm that originates from the Schwann cells or the neural crest-derived cells in the tongue. This tumor is composed of granular cells with abundant eosinophilic cytoplasm and large nuclei.
**Why the Correct Answer is Right**
The granular cell myoblastoma is thought to arise from the neural crest-derived cells that are present in the tongue. The tumor cells are characterized by their granular appearance under the microscope due to the accumulation of lysosomes and other organelles. The histological features of granular cell myoblastoma include large, polygonal cells with abundant eosinophilic cytoplasm and large nuclei, which is a distinctive feature that helps in differentiating it from other types of tumors.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because granular cell myoblastoma is not a type of lymphoma. Lymphomas are a group of cancers that arise from the lymphoid cells, whereas granular cell myoblastoma originates from the neural crest-derived cells.
**Option B:** This option is incorrect because granular cell myoblastoma is not a type of carcinoma. Carcinomas are a group of cancers that arise from the epithelial cells, whereas granular cell myoblastoma originates from the neural crest-derived cells.
**Option C:** This option is incorrect because granular cell myoblastoma is not a type of melanoma. Melanomas are a group of cancers that arise from the melanocytes, whereas granular cell myoblastoma originates from the neural crest-derived cells.
**Clinical Pearl / High-Yield Fact**
Granular cell myoblastoma is a rare, benign tumor that can occur in various parts of the body, including the tongue, but it is most commonly found in the tongue. It is essential to differentiate it from other types of tumors, such as lymphomas and carcinomas, based on its histological features.
**Correct Answer:** D.