Gold standard investigation for diagnosis of insulinoma –
Correct Answer: 72 hrs fasting
Description: Pathology of pancreatic endocrine tumor (insulinoma). Specialty. Oncology. An insulinoma is a tumor of the pancreas that is derived from beta cells and secretes insulin. It is a rare form of a neuroendocrine tumor The diagnosis of insulinoma is suspected in a patient with symptomatic fasting hypoglycemia. The conditions of Whipple's triad need to be met for the diagnosis of "true hypoglycemia" to be made: symptoms and signs of hypoglycemia, concomitant p 72 hrs fasting blood glucose level of 45 mg/dL (2.5 mmol/L) or less, and reversibility of symptoms with administration of glucose. Ref Davidson edition23rd pg834
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