GNAS mutation is associated with malignancy of
Correct Answer: Somatotrophs
Description: GNAS encodes for alpha subunit of stimulatory G-protein , Gsalpha . Oncogenic activation of GNAS constitutively activates Gsalpha leading to Growth hormone(GH) adenomas. Ref: Robbins and cotrans 9e Pg 1076
Category:
Pathology
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