**Core Concept**
When glucose is broken down in glycolysis under anaerobic conditions, the process produces a specific end product that can be used by cells to maintain energy levels in the absence of oxygen.
**Why the Correct Answer is Right**
Under anaerobic conditions, the enzyme pyruvate kinase is inhibited, and the pyruvate molecule is converted to lactate by the enzyme lactate dehydrogenase. This reaction is necessary to regenerate NAD+ from NADH, which is essential for glycolysis to continue. The production of lactate is a critical adaptation that allows cells to maintain energy production in the absence of oxygen. This is a vital mechanism for cells to survive in low-oxygen environments, such as during intense physical activity or in ischemic conditions.
**Why Each Wrong Option is Incorrect**
**Option B:** Pyruvic acid is the end product of glycolysis under aerobic conditions, not anaerobic conditions. In the presence of oxygen, pyruvate is fed into the citric acid cycle for further energy production.
**Option C:** Acetoacetic acid is a ketone body produced in the liver from acetyl-CoA under fasting or ketogenic conditions. It is not related to glycolysis under anaerobic conditions.
**Option D:** Oxaloacetic acid is a key intermediate in the citric acid cycle and gluconeogenesis, but it is not the end product of glycolysis under anaerobic conditions.
**Clinical Pearl / High-Yield Fact**
In conditions of prolonged anaerobic metabolism, such as in lactic acidosis, the accumulation of lactate can lead to metabolic acidosis, which can have severe consequences if not promptly treated.
**β Correct Answer: A. Lactic acid**
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