**Core Concept**
Skeletal muscle glycogen storage diseases are a group of inherited disorders characterized by the deficiency of enzymes involved in glycogen metabolism. During strenuous exercise, skeletal muscle undergoes intense glycolysis, leading to the depletion of glycogen stores and the accumulation of lactic acid, which causes muscle fatigue and soreness.

**Why the Correct Answer is Right**
The correct answer is associated with McArdle's disease, also known as Glycogen Storage Disease Type V (GSD V). McArdle's disease is caused by a deficiency of the enzyme myophosphorylase, which is responsible for the breakdown of glycogen to glucose-1-phosphate in skeletal muscle. As a result, skeletal muscle is unable to utilize glycogen as a fuel source during exercise, leading to the accumulation of lactic acid and a decrease in muscle pH. However, the alkaline pH in the question is incorrect as it contradicts the expected acidic pH in McArdle's disease.

**Why Each Wrong Option is Incorrect**
**Option A:** Pompe disease is caused by a deficiency of acid alpha-glucosidase, leading to the accumulation of glycogen in lysosomes, but it is not associated with muscle alkalosis during exercise.

**Option B:** Cori's disease is caused by a deficiency of debranching enzyme, which is involved in the breakdown of glycogen to glucose-1-phosphate in liver and muscle. It does not specifically cause muscle alkalosis during exercise.

**Option C:** Hers' disease is caused by a deficiency of liver phosphorylase, which is involved in the breakdown of glycogen to glucose-1-phosphate in the liver. It does not specifically cause muscle alkalosis during exercise.

**Clinical Pearl / High-Yield Fact**
The clinical presentation of McArdle's disease includes muscle cramps, weakness, and fatigue during exercise, which are relieved by rest. The disease is inherited in an autosomal recessive pattern, and genetic testing can confirm the diagnosis.

**Correct Answer:** None