GLUT receptor on pancreas is?
**Core Concept**
The GLUT receptor, also known as the glucose transporter, is a family of proteins responsible for facilitating the transport of glucose across cell membranes. In the pancreas, the GLUT receptor plays a crucial role in glucose sensing, which triggers the release of insulin and glucagon hormones.
**Why the Correct Answer is Right**
In the pancreas, the GLUT receptor specifically refers to GLUT2, a type of facilitative diffusion glucose transporter. GLUT2 is responsible for the high-capacity, low-affinity transport of glucose across the beta-cell membrane, allowing for rapid glucose sensing and insulin release. This process is essential for maintaining glucose homeostasis.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because GLUT1 is primarily involved in basal glucose transport in the brain, red blood cells, and placenta.
**Option B:** Incorrect because GLUT4 is primarily involved in insulin-regulated glucose transport in adipose tissue and skeletal muscle.
**Option C:** Incorrect because GLUT3 is primarily involved in high-affinity glucose transport in neurons and other tissues.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that the GLUT2 receptor on pancreatic beta-cells is responsible for glucose-induced insulin secretion, which is a critical mechanism in the regulation of blood glucose levels.
**Correct Answer: D. GLUT2.**