**Core Concept**
The GLUT 4 receptors are a type of glucose transporter that plays a crucial role in glucose homeostasis by facilitating the uptake of glucose into cells in response to insulin signaling. This process is essential for maintaining normal blood glucose levels.

**Why the Correct Answer is Right**
GLUT 4 receptors are primarily found in adipose tissue and striated muscle, including skeletal muscle and cardiac muscle. They are responsible for insulin-regulated glucose uptake, which is critical for energy metabolism and glucose homeostasis. In response to insulin binding to its receptor, GLUT 4 translocates from intracellular vesicles to the plasma membrane, increasing glucose uptake into these cells.

**Why Each Wrong Option is Incorrect**
**Option A:** While GLUT 4 receptors are involved in glucose metabolism, they are not primarily found in liver tissue, which expresses GLUT 2 receptors.
**Option B:** Brain tissue expresses GLUT 1, GLUT 3, and GLUT 5 receptors, but not primarily GLUT 4 receptors.
**Option C:** Pancreatic beta cells express GLUT 2 receptors, which are involved in glucose sensing and insulin secretion, but not primarily GLUT 4 receptors.

**Clinical Pearl / High-Yield Fact**
The translocation of GLUT 4 receptors to the plasma membrane in response to insulin signaling is a crucial mechanism for regulating glucose uptake in adipose and striated muscle tissue, making it a key target for the treatment of type 2 diabetes.

**Correct Answer:** C. Striated muscle, including skeletal muscle and cardiac muscle.