Glucose is absorbed into the epithelial cells lining the mucous membrane of the small intestine from their brush border surface by an active transpo mechanism Sodium co-transpo mechanism. Binding of glucose & Na+ to carrier protein: The carrier protein in cell membrane has 2 binding sites, one for sodium & another for glucose.It is called sodium-dependent glucose transpoer-I. The conformational change in the carrier protein occurs only when the binding sites are occupied by the sodium & glucose present in the gut lumen forming the sodium- glucose - carrier complex. Ref: Medical Physiology, Indu Khurana