**Core Concept**
Minimal change glomerulopathy is a type of kidney disease characterized by the loss of foot processes of the podocytes and the presence of podocyte effacement. It is often associated with nephrotic syndrome, a condition marked by massive proteinuria, hypoalbuminemia, and edema.
**Why the Correct Answer is Right**
Hepatitis B is not typically associated with minimal change glomerulopathy. The correct associations for minimal change disease include infections like HIV (B), malignancies like Hodgkin's disease (D), and certain drugs that induce interstitial nephritis (C). Hepatitis B is more commonly linked to membranous nephropathy or membranoproliferative glomerulonephritis. The immune complex deposition and subsequent inflammation in Hepatitis B lead to different glomerular damage patterns.
**Why Each Wrong Option is Incorrect**
**Option A:** Hepatitis B is not commonly associated with minimal change glomerulopathy, which is characterized by podocyte effacement and foot process loss.
**Option B:** HIV is indeed associated with minimal change glomerulopathy, as it can trigger immune complex deposition and subsequent glomerular damage.
**Option C:** Certain drugs can induce interstitial nephritis, which may lead to minimal change disease, as part of a broader spectrum of kidney damage.
**Option D:** Hodgkin's disease has been linked to minimal change glomerulopathy, possibly due to immune complex deposition and subsequent glomerular damage.
**Clinical Pearl / High-Yield Fact**
When approaching a patient with nephrotic syndrome, remember that minimal change disease is the most common cause, especially in children, but also consider other glomerular diseases associated with infections, malignancies, or drugs.
**β Correct Answer: A. Hepatitis B**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.