**Core Concept**
The glomerular filtration rate (GFR) determines the rate at which small molecules are filtered from the blood into the renal tubules. The size of molecules, particularly their molecular weight, influences their ability to pass through the glomerular filtration barrier.

**Why the Correct Answer is Right**
The glomerular filtration barrier consists of the fenestrated endothelium, the glomerular basement membrane, and the podocytes. Molecules smaller than 5-6 nanometers can pass through the glomerular filtration barrier. Protein molecules, such as albumin, have a molecular weight of approximately 69 kDa and a size of around 3.5 nanometers. However, larger molecules like immunoglobulins (IgG) have a molecular weight of around 150 kDa and a size of approximately 10 nanometers, making them too large to pass through the glomerular filtration barrier.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is not provided.
* **Option B:** This option is not provided.
* **Option C:** This option is not provided.
* **Option D:** This option is not provided.

**Clinical Pearl / High-Yield Fact**
The glomerular filtration rate is directly proportional to the surface area of the glomeruli and inversely proportional to the thickness of the glomerular basement membrane.

**Correct Answer:** D.