## Core Concept
Generalized transducing phages, such as phage P1, are viruses that infect bacteria and can transfer bacterial DNA from one bacterium to another. This process is known as transduction. Phage P1 is a well-studied example of a generalized transducing phage.
## Why the Correct Answer is Right
Generalized transducing phages like P1 can package random fragments of the bacterial chromosome into their phage particles. When these phage particles infect another bacterium, they can transfer the bacterial DNA they carry. This is a significant mechanism of horizontal gene transfer in bacteria. Phage P1, specifically, is known for its ability to mediate generalized transduction in *E. coli*, making it a valuable tool in bacterial genetics for mapping genes and studying bacterial genetics.
## Why Each Wrong Option is Incorrect
- **Option A:** This option is incorrect because generalized transducing phages do not require specific bacterial mutants to facilitate transduction; they can transfer any part of the bacterial chromosome.
- **Option B:** This option is incorrect because while specialized transducing phages can only transfer specific genes, generalized transducing phages like P1 can transfer any bacterial gene.
- **Option C:** This option might seem plausible but is incorrect in the context of the question because generalized transducing phages are indeed capable of transferring bacterial DNA between bacteria, which is a form of genetic recombination.
## Clinical Pearl / High-Yield Fact
A key point to remember is that generalized transduction, mediated by phages like P1, is a critical method for genetic mapping and understanding bacterial genetics. It's also a mechanism by which bacteria can acquire new traits, such as antibiotic resistance.
## Correct Answer Line
**Correct Answer: D.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.