Which of the following organism causes Gastrointestinal enteritis necroticans?
**Core Concept**
Gastrointestinal enteritis necroticans, also known as pigbel disease, is a severe form of enteritis caused by a bacterial infection. The condition is characterized by necrosis of the intestinal mucosa, leading to severe abdominal pain, diarrhea, and potentially life-threatening complications.
**Why the Correct Answer is Right**
The correct answer is Clostridium perfringens type C, a bacterium that produces a toxin responsible for the disease. This toxin causes necrosis of the intestinal mucosa by damaging the cellular membranes, leading to the characteristic symptoms of enteritis necroticans. The condition is typically seen in individuals who consume undercooked or raw meat, particularly pork, contaminated with the bacteria.
**Why Each Wrong Option is Incorrect**
**Option A:** Clostridium difficile is a different bacterium that causes pseudomembranous colitis, a condition characterized by inflammation and ulcers in the colon. It is not associated with enteritis necroticans.
**Option B:** Campylobacter species are a common cause of gastroenteritis, but they do not cause the severe necrotizing enteritis seen with Clostridium perfringens type C.
**Option C:** Escherichia coli (E. coli) can cause a range of gastrointestinal infections, including enteritis, but it is not the primary cause of enteritis necroticans.
**Clinical Pearl / High-Yield Fact**
Clostridium perfringens type C is a foodborne pathogen that can cause severe gastrointestinal disease. Individuals who consume undercooked or raw meat, particularly pork, are at increased risk of infection. It is essential to practice proper food handling and cooking techniques to prevent the spread of this disease.
**Correct Answer:** C. Clostridium perfringens type C.