**Core Concept**
Ganglion of tendons is a type of lesion that occurs in the wrist or other joints, characterized by a soft, painless, and usually movable mass. It arises from the degeneration of the fibrous tissue within the tendon sheath, leading to the accumulation of mucinous fluid and the formation of a ganglion cyst.

**Why the Correct Answer is Right**
Myxomatous degeneration refers to the process of degeneration of connective tissue, leading to the accumulation of mucin and the formation of a gelatinous mass. In the context of ganglion of tendons, myxomatous degeneration occurs due to the repetitive stress and strain on the tendons, leading to the breakdown of the fibrous tissue and the formation of a ganglion cyst. This process is often associated with the tendons of the wrist, particularly the flexor tendons, and is a common cause of wrist pain and swelling.

**Why Each Wrong Option is Incorrect**
**Option A:** Neoplastic process - Ganglion of tendons is not a neoplastic process, meaning it is not a tumor or a cancerous growth. While it may appear as a mass, it is a degenerative process rather than a neoplastic one.
**Option B:** Malformation - Ganglion of tendons is not a congenital malformation, meaning it is not a defect present at birth. It is a acquired condition that develops over time due to repetitive stress and strain on the tendons.
**Option C:** Amyloid deposition - Amyloid deposition refers to the accumulation of amyloid protein in tissues, which is a characteristic of certain diseases such as amyloidosis. This is not a feature of ganglion of tendons.

**Clinical Pearl / High-Yield Fact**
Ganglion of tendons often presents as a soft, painless, and movable mass on the wrist, but it can also be associated with pain and swelling. It is essential to distinguish ganglion of tendons from other wrist masses, such as ganglion cysts, which are a type of mucinous cyst that can be associated with joint degeneration.

**✓ Correct Answer: D. Myxomatous degeneration**