G-6-PD deficiency causes –
Correct Answer: Hemolytic anemia
Description: Ans. is 'b' i.e., Hemolytic anemia o The enzyme glucose-6-phosphate dehydrogenase (G6PDQ) may be deficient in some persons,o It is the most common enzyme deficiency seen in clinical practiceQ. The defect is transmitted as x-linkedrecessive trait.o This defect results in impairment of HMP shunt with reduced generation of NADPHQ.o Thus, glutathione can not be reduced as it requires NADPH.o This, in turn, results in red cell hemolysis (hemolytic anemia) in response to oxidative stress.
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now