Function of UGA codon –
**Core Concept**
The UGA codon is a type of stop codon in the genetic code, responsible for terminating protein synthesis. It plays a crucial role in the process of translation, ensuring that the ribosome knows when to stop adding amino acids to the growing polypeptide chain.
**Why the Correct Answer is Right**
The UGA codon is recognized by a specific class of transfer RNA (tRNA) molecules that are designed to bind to this stop codon. When the ribosome encounters the UGA codon, it recruits a release factor, which interacts with the tRNA to facilitate the release of the completed polypeptide chain from the ribosome. This process is essential for the proper regulation of protein synthesis and the prevention of aberrant protein production.
**Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because it does not accurately describe the function of the UGA codon. While some codons do code for specific amino acids, the UGA codon is a stop signal.
- **Option B:** This option is incorrect because it implies that the UGA codon codes for a specific amino acid, which is not the case. The UGA codon is a stop codon, not a sense codon.
- **Option C:** This option is incorrect because it suggests that the UGA codon is involved in the initiation of protein synthesis, which is not accurate. The UGA codon is a stop signal, not a start signal.
**Clinical Pearl / High-Yield Fact**
The UGA codon is one of three stop codons in the genetic code, along with UAA and UAG. Understanding the function of stop codons is crucial for grasping the process of translation and the regulation of protein synthesis.
**Correct Answer:** D.