**Core Concept**
Fumarase is an enzyme involved in the citric acid cycle, also known as the Krebs cycle or tricarboxylic acid cycle. This cycle is a key metabolic pathway that generates energy through the oxidation of acetate derived from carbohydrates, fats, and proteins. Fumarase catalyzes the hydration and dehydration reaction of fumarate to malate.
**Why the Correct Answer is Right**
The correct answer is related to the function of fumarase in the citric acid cycle. Fumarase catalyzes the reversible hydration of fumarate to form L-malate, a crucial step in the cycle. This reaction is important for the regeneration of NAD+ and the continuation of the cycle.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not accurately describe the role of fumarase.
**Option B:** This option is also incorrect as it misrepresents the enzymatic function.
**Option C:** This is not accurate regarding fumarase's activity in the citric acid cycle.
**Clinical Pearl / High-Yield Fact**
Fumarase deficiency is a rare genetic disorder that affects the citric acid cycle, leading to elevated levels of fumarate in the blood and urine. This condition highlights the importance of fumarase in normal metabolic function.
**Correct Answer:** D. an enzyme in the citric acid cycle that converts fumarate to malate.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.