Fox Fordyce’s disease is a disease of-
**Core Concept**
Fox-Fordyce disease is a rare, chronic condition characterized by the blockage of apocrine sweat glands, leading to the development of itchy, painful bumps on the skin, particularly in the axillary and pubic regions.
**Why the Correct Answer is Right**
This condition is caused by the obstruction of apocrine sweat glands due to the accumulation of keratin and other cellular debris. The apocrine glands, which are responsible for producing a type of sweat that is rich in protein and lipids, become clogged, leading to inflammation and the formation of painful bumps. The exact cause of the blockage is unknown, but it is thought to be related to an imbalance in the normal functioning of the apocrine glands.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because Fox-Fordyce disease primarily affects the apocrine sweat glands, not the eccrine glands.
**Option B:** This option is incorrect because Fox-Fordyce disease is not a form of folliculitis, which is an inflammation of the hair follicles.
**Option C:** This option is incorrect because Fox-Fordyce disease is not a type of eczema, although it can present with similar symptoms such as itching and inflammation.
**Clinical Pearl / High-Yield Fact**
Fox-Fordyce disease is often misdiagnosed as eczema, folliculitis, or acne, so a high index of suspicion is necessary to diagnose this condition accurately.
**Correct Answer: D. Apocrine sweat glands**