**Core Concept**
Uric acid is a waste product formed in the body as a result of purine metabolism. Purines are nitrogenous bases found in DNA and RNA, and their breakdown leads to the formation of uric acid.
**Why the Correct Answer is Right**
Uric acid is formed through the catabolism of purines by the enzyme xanthine oxidase. This enzyme catalyzes the oxidation of hypoxanthine to xanthine and then xanthine to uric acid. The process occurs mainly in the liver and involves the sequential action of xanthine oxidase and other enzymes. The byproduct of this reaction is uric acid, which is then excreted by the kidneys.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as it is not a well-known pathway for uric acid formation.
**Option B:** This option is incorrect as it is not directly related to the formation of uric acid from purine metabolism.
**Option C:** This option is incorrect as it is a different metabolic pathway and is not responsible for uric acid formation.
**Clinical Pearl / High-Yield Fact**
It is essential to note that excessive uric acid levels can lead to the development of gout, a type of arthritis characterized by the deposition of urate crystals in joints. This condition is often associated with high blood pressure, obesity, and kidney disease.
**Correct Answer:** C. Purine metabolism via xanthine oxidase.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.