For Ca Anal canal t/t of choice is –
Correct Answer: Chemoradiation
Description: Nigro regimen refers to combined chemotherapy and radiotherapy for primary treatment of malignant tumors of the anal canal.
In the 1970s, Nigro pioneered preoperative combination chemoradiation therapy to convert unrespectable cases to respective cases. There was no surgical pathological evidence of tumor found in three out of three patients treated with this approach in an early report.
This led to the concept of definitive radiation therapy combined with chemotherapy. Prior to this, the standard definitive treatment for carcinoma of the anal canal was abdominal-perineal resection, which necessitated a permanent colostomy.
The organ preservation concept following the discovery of a high complete response rate from combined chemoradiation saves a large number of patients from undergoing abdominal-perineal resection and colostomy.
Category:
Surgery
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now