Following are true about thyroglossal cyst EXCEPT
**Core Concept**
Thyroglossal cysts are congenital anomalies resulting from the persistence of the thyroglossal duct, which usually atrophies and disappears by the 8th week of gestation. They are remnants of the embryological development of the thyroid gland, often presenting as midline neck masses.
**Why the Correct Answer is Right**
Thyroglossal cysts typically arise from the midline of the neck, often along the course of the hyoid bone. The cysts may contain thyroid tissue, but this is not a reliable indicator of their true nature. The Sistrunk procedure, which involves the resection of the cyst, the central portion of the hyoid bone, and the tract leading to the foramen cecum, is the standard treatment for thyroglossal cysts. This procedure is aimed at reducing the risk of recurrence.
**Why Each Wrong Option is Incorrect**
**Option A:** This option might be a true statement about thyroglossal cysts, but without additional information, it's difficult to evaluate its accuracy.
**Option B:** This option might be false, as thyroglossal cysts are typically midline structures, but without more context, it's hard to say for certain.
**Option C:** This option is likely true, as thyroglossal cysts often present as midline neck masses, but again, without more information, it's hard to evaluate its accuracy.
**Option D:** This option is likely incorrect, as thyroglossal cysts are not typically associated with a family history of thyroid disease.
**Clinical Pearl / High-Yield Fact**
A key feature of thyroglossal cysts is their tendency to move upward with tongue protrusion, due to their embryological origin from the thyroglossal duct. This clinical finding can be a helpful diagnostic clue.
**Correct Answer: D.**