True about fluorescent antibody detection test in diagnosis of Plasmodium falcifarum are all except ?
**Core Concept**
The fluorescent antibody detection test, also known as the direct fluorescent antibody (DFA) test, is a laboratory method used for the detection and identification of Plasmodium species, including Plasmodium falciparum. This test utilizes fluorescent-labeled antibodies to detect specific antigens present on the surface of malaria parasites.
**Why the Correct Answer is Right**
The DFA test is a sensitive and specific method for diagnosing Plasmodium falciparum infections. The fluorescent-labeled antibodies bind to specific antigens on the surface of the parasites, resulting in a visible fluorescence under ultraviolet light. This test is particularly useful in areas where malaria is endemic, as it can be performed on peripheral blood smears, making it a valuable tool for rapid diagnosis and surveillance.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because the DFA test is indeed used for the diagnosis of Plasmodium falciparum. There is no evidence to suggest that it is not used for this purpose.
* **Option B:** This option is incorrect because the DFA test is a widely accepted and validated method for diagnosing malaria, including P. falciparum. There is no credible evidence to suggest that it is not a reliable method.
* **Option C:** This option is incorrect because the DFA test can be performed on peripheral blood smears, making it a valuable tool for rapid diagnosis and surveillance in areas where malaria is endemic.
**Clinical Pearl / High-Yield Fact**
The DFA test is a rapid and sensitive method for diagnosing malaria, including P. falciparum, and can be performed on peripheral blood smears, making it a valuable tool for rapid diagnosis and surveillance in areas where malaria is endemic.
**Correct Answer: C.**