Pathology First pathological change apparent in Nephrotic syndrome is A Thickening of the glomerular capillary wall and effacement of podocyte foot processes B Segmental sclerosis of glomerulus C Break in basement membrane D Mononuclear infiltration 💡 Explanation First pathological change apparent in Nephrotic syndrome is ✓ Correct Answer: A. Thickening of the glomerular capillary wall and effacement of podocyte foot processes