**Core Concept**
Fever in burnt patients is a complex phenomenon involving the interplay of various physiological and pathological processes. The release of pyrogens, such as endotoxins and cytokines, plays a crucial role in the development of fever in this population. The hypothalamic-pituitary-adrenal axis and the sympathetic nervous system also contribute to the regulation of body temperature.
**Why the Correct Answer is Right**
The correct answer is related to the systemic inflammatory response syndrome (SIRS) that occurs in burnt patients. The release of endotoxins from the burnt tissue triggers an inflammatory response, leading to the production of cytokines such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1Ξ²). These cytokines stimulate the hypothalamus, causing an increase in the body's temperature set point, resulting in fever.
Option A:
*Option A is incorrect because it does not accurately describe the primary cause of fever in burnt patients.*
Option B:
*Option B is incorrect because it is a manifestation of the systemic inflammatory response, rather than the primary cause of fever.*
Option C:
*Option C is incorrect because it is a complication of severe burns, but not the primary cause of fever.*
**Clinical Pearl / High-Yield Fact**
Burnt patients are at risk of developing hypermetabolism, which can lead to increased energy expenditure and malnutrition. Early nutritional support is crucial in managing these patients.
**Correct Answer: C. Septicaemia**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.