Feature of glomerular haematuria
The question is asking for a feature of glomerular hematuria. Glomerular hematuria is when red blood cells pass through the glomerular basement membrane, which causes them to be fragmented. This results in dysmorphic RBCs in the urine. Also, they might show red cell casts, which are pathognomonic for glomerulonephritis.
So possible correct features would be dysmorphic RBCs, red cell casts, associated with conditions like glomerulonephritis. Let me think of common wrong options. Maybe they might confuse it with non-glomerular hematuria, which would have intact RBCs and no casts.
The correct answer is likely an option that mentions dysmorphic RBCs or red cell casts. Let's say the options are:
A. Uniform RBCs in urine
B. Presence of red cell casts
C. Associated with UTI
D. Normal sediment on urinalysis
Then the correct answer would be B. Presence of red cell casts. The explanation would need to highlight that glomerular hematuria is characterized by dysmorphic RBCs and red cell casts, whereas non-glomerular (e.g., from UTI) would have normal RBCs.
Now, I need to structure the explanation according to the given sections. Core concept would be the difference between glomerular and non-glomerular hematuria. Why correct is right: red cell casts are pathognomonic. Why wrong: A is incorrect because glomerular RBCs are dysmorphic, not uniform. C is wrong because UTI is non-glomerular. D is incorrect because sediment is abnormal.
Clinical pearl: Remember red cell casts in glomerulonephritis. Correct answer line would be B.
**Core Concept**
Glomerular hematuria occurs when erythrocytes pass through a damaged glomerular basement membrane, leading to **dysmorphic red blood cells** and **red blood cell casts** in urine. This distinguishes it from non-glomerular hematuria (e.g., from urinary tract infections or stones), which presents with normal RBC morphology.
**Why the Correct Answer is Right**
**Option B** (Presence of red cell casts) is correct because red cell casts form when RBCs pass through a damaged glomerulus and become trapped in tubular fluid. These casts are **pathognomonic** for glomerulonephritis. The dysmorphic RBCs (from shearing in the basement membrane) further confirm glomerular origin.
**Why Each Wrong Option is Incorrect**
**Option A:** Uniform RBCs suggest non-glomerular bleeding (e.g., urothelium) due to intact basement membranes.
**Option C:** Urinary tract infections cause non-glomerular hematuria; RBCs remain normal in shape.
**Option D:** Glomerular hematuria always shows abnormal urine sediment (e.g., RBC casts