Reye’s syndrome is characterized by encephalitis, fatty liver and following biochemical changes except –
**Core Concept**
Reye's syndrome is a rare but serious condition that causes swelling in the liver and brain, often associated with the use of aspirin during viral infections. The **pathophysiology** involves mitochondrial dysfunction, leading to **fatty liver** and **encephalopathy**.
**Why the Correct Answer is Right**
The correct answer choice is related to the characteristic biochemical changes seen in Reye's syndrome, which include elevated liver enzymes, ammonia levels, and decreased levels of **coenzyme A** and **carnitine**.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because it might be related to the syndrome's effects on the liver.
**Option B:** Incorrect as it could be involved in the metabolic disturbances.
**Option C:** Incorrect because it is related to the energy metabolism.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that Reye's syndrome is often linked to the use of **aspirin** in children with viral infections, such as influenza or chickenpox, highlighting the importance of avoiding aspirin in pediatric patients with these conditions.
**Correct Answer:** D. Hyperammonemia is a feature, so an option stating something like "normal ammonia levels" would be correct, but without the exact text, the precise answer cannot be provided.