**Core Concept**
Long chain fatty acids require a carrier to penetrate the inner mitochondrial membrane, which is impermeable to them. This process is crucial for the breakdown of fatty acids in the mitochondria during beta-oxidation.
**Why the Correct Answer is Right**
The correct answer involves a protein called carnitine palmitoyltransferase 1 (CPT1), which facilitates the transfer of long chain fatty acids from coenzyme A (CoA) to carnitine. This step is essential for the transport of long chain fatty acids across the inner mitochondrial membrane. The carnitine-fatty acid ester then undergoes a series of reactions, ultimately leading to the conversion of the fatty acid into acyl-CoA, which can then undergo beta-oxidation.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not specify the role of carnitine in the transport of long chain fatty acids across the inner mitochondrial membrane.
**Option B:** This option is incorrect because it is not a known mechanism for the transport of long chain fatty acids across the inner mitochondrial membrane.
**Option C:** This option is incorrect because it is not a specific enough answer and does not accurately describe the role of carnitine in the transport of long chain fatty acids.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that the transport of long chain fatty acids into the mitochondria is dependent on the availability of carnitine and the activity of CPT1. This knowledge is crucial for understanding the regulation of beta-oxidation and the effects of various metabolic disorders on fatty acid metabolism.
**Correct Answer: C. Carnitine**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.