In a population of 2000, 20 cases had disease, out of which 5 had died. Case fatality rate of disease is ?
**Core Concept**
Case fatality rate (CFR) is a measure of the severity of a disease, defined as the proportion of deaths within a population of people with a particular condition, over a specific time period. It is calculated as the number of deaths due to the disease, divided by the number of cases of the disease, multiplied by 100 to express the rate as a percentage.
**Why the Correct Answer is Right**
To calculate the case fatality rate, we use the formula: CFR = (Number of deaths due to the disease / Number of cases of the disease) x 100. In this scenario, the number of deaths due to the disease is 5, and the number of cases of the disease is 20. Therefore, the case fatality rate is (5 / 20) x 100 = 25%. This means that 25% of people with the disease died from it.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is not provided.
**Option B:** This option is not provided.
**Option C:** This option is not provided.
**Option D:** This option is not provided.
**Clinical Pearl / High-Yield Fact**
Remember that case fatality rate is a useful measure of disease severity, but it is not the same as mortality rate, which is the proportion of deaths in the entire population, not just those with the disease.
**Correct Answer: D. 25%.**