Fat mesentery is sent for investigation in which poisoning –
**Core Concept**
The fat mesentery is a key site for the storage of lipophilic substances, including certain drugs and toxins. In cases of suspected poisoning, the fat mesentery can accumulate and concentrate these substances, making it a valuable specimen for toxicological analysis.
**Why the Correct Answer is Right**
In cases of organophosphate poisoning, the fat mesentery is sent for investigation to detect the accumulation of organophosphate residues. This is because organophosphates are lipophilic compounds that can bind to and accumulate in fatty tissues, including the fat mesentery. The detection of these residues in the fat mesentery can provide valuable evidence of exposure to organophosphates. The enzyme acetylcholinesterase is also inhibited by organophosphates, leading to an accumulation of acetylcholine in the neuromuscular junction, causing muscle weakness and paralysis.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the fat mesentery is not typically sent for investigation in cases of carbon monoxide poisoning, which is suspected based on clinical presentation and measurement of carboxyhemoglobin levels in blood.
**Option B:** This option is incorrect because the fat mesentery is not typically sent for investigation in cases of barbiturate poisoning, which is suspected based on clinical presentation and measurement of barbiturate levels in blood and urine.
**Option C:** This option is incorrect because the fat mesentery is not typically sent for investigation in cases of heavy metal poisoning, which is suspected based on clinical presentation and measurement of heavy metal levels in blood, urine, and hair.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that the fat mesentery can accumulate and concentrate lipophilic substances, making it a valuable specimen for toxicological analysis in cases of suspected poisoning.
**Correct Answer:** C.