False statement about Pseudomynoma peritonei is
**Core Concept**
Pseudomyxoma peritonei (PMP) is a clinical syndrome characterized by recurrent mucinous ascites causing abdominal distension. It is often associated with a primary mucinous tumor, usually of the appendix, which ruptures and seeds the peritoneal cavity with mucin-producing cells.
**Why the Correct Answer is Right**
PMP is a type of peritoneal dissemination of a mucinous tumor, which typically arises from a primary appendiceal tumor. The mucin-producing cells in the peritoneal cavity lead to a gradual accumulation of mucin, causing abdominal distension. The condition is often associated with a high level of CA 125, a tumor marker that can be used for diagnosis and monitoring.
**Why Each Wrong Option is Incorrect**
**Option A:** PMP is not typically associated with a primary ovarian tumor.
**Option B:** PMP is not characterized by a high level of CA 19-9, a tumor marker more commonly associated with pancreatic cancer.
**Option C:** PMP does not typically present with a high level of CEA, a tumor marker more commonly associated with colorectal cancer.
**Clinical Pearl / High-Yield Fact**
The Whipple's triad, which includes abdominal pain, a palpable abdominal mass, and elevated CA 125 levels, is often used to diagnose PMP. A high index of suspicion is necessary for early diagnosis, as the condition can mimic other peritoneal disorders.
**Correct Answer: D**