False statement about extra adrenal pheochromocytoma –
Correct Answer: Constitute 50% of total
Description: Extra-adrenal pheochromocytomas may arise in any poion of the paraganglion system, although they most commonly occur below the diaphragm. The most common site of occurrence of extra-adrenal pheochromocytoma is the superior para-aoic region between the diaphragm and lower renal poles. Although the traditional teaching has been that 10% of all pheochromocytomas are at extra-adrenal sites, this may be an underestimation. Extra-adrenal pheochromocytomas probably represent at least 15% of adult and 30% of childhood pheochromocytomas. They may be malignant in up to 40% of the cases, although conflicting data add to the unceainty of this point. Patients with tumors arising at extra-adrenal sites commonly present with headache, palpitations, sweating and hypeension. The diagnosis is most often confirmed by demonstrating increased catecholamine production, usually by measurement of urinary catecholamines and/or their metabolites. Ref - ( Harrison 17 pg 2269) , pubmed.com , <a href="
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