## **Core Concept**
Goodpasture's disease, also known as anti-glomerular basement membrane (anti-GBM) disease, is a rare autoimmune disorder characterized by the production of antibodies against the glomerular and alveolar basement membranes. This leads to inflammation and damage in the kidneys and lungs. The disease is caused by the formation of autoantibodies against the α3 chain of type IV collagen.

## **Why the Correct Answer is Right**
The correct answer, ., implies that option C is the statement that is false about Goodpasture's disease. To validate this, we need to assess each option based on known facts about Goodpasture's disease.

## **Why Each Wrong Option is Incorrect**
- **Option A:** Typically, Goodpasture's disease involves the production of anti-GBM antibodies, which target the basement membrane of the glomeruli in the kidneys and sometimes the lungs, leading to glomerulonephritis and pulmonary hemorrhage. If option A states a known fact about Goodpasture's, then it is incorrect as the false statement.
- **Option B:** If option B accurately describes a characteristic of Goodpasture's disease, such as its pathophysiology or clinical presentation, then it is not the false statement.
- **Option D:** Similarly, if option D is a true statement regarding Goodpasture's disease, it cannot be the false statement.

## **Clinical Pearl / High-Yield Fact**
A key clinical pearl about Goodpasture's disease is that it often presents with a combination of renal and pulmonary symptoms, such as rapidly progressive glomerulonephritis and pulmonary hemorrhage. Early diagnosis and treatment, usually with plasmapheresis and immunosuppressive therapy, are critical to improve outcomes.

## **Correct Answer: C.**