**Core Concept**
Alcohol-induced neurotoxicity can cause a range of neurological deficits, including ataxia and ophthalmoplegia (weakness or paralysis of the extraocular muscles). The patient's presentation suggests a history of Wernicke's encephalopathy, a condition characterized by the triad of ataxia, ophthalmoplegia, and confusion.
**Why the Correct Answer is Right**
The expected outcome in a patient with Wernicke's encephalopathy who receives treatment is the resolution of the acute symptoms, including ophthalmoplegia. This is due to the administration of thiamine (vitamin B1), which is essential for the proper functioning of the nervous system. Thiamine deficiency is the underlying cause of Wernicke's encephalopathy, and supplementation helps to reverse the neurotoxic effects of alcohol.
**Why Each Wrong Option is Incorrect**
**Option A:** Progression to Korsakoff's psychosis is a possible outcome in patients with Wernicke's encephalopathy if treatment is delayed or inadequate. However, it is not the expected outcome in a patient who has received proper treatment.
**Option B:** Residual ataxia in 50% of patients is a possible outcome, but it is not the expected outcome in a patient who receives timely and adequate treatment.
**Option C:** Extraocular palsy may take several days to resolve, even with treatment, and may not disappear within an hour.
**Option D:** Immediate relief from symptoms is not always possible, as the resolution of ataxia and ophthalmoplegia can take several days to weeks with treatment.
**Clinical Pearl / High-Yield Fact**
The progression from Wernicke's encephalopathy to Korsakoff's psychosis can be prevented with prompt and adequate treatment. Thiamine supplementation is essential in the management of Wernicke's encephalopathy, and it should be administered as soon as possible to prevent long-term neurological damage.
**Correct Answer: C. Extraocular palsy disappear in hour**
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