**Question:** A young man aged 30 years, presents with difficulty in vision in the left eye for the last 10 days. He is a rural community and gives history of trauma to his left eye with vegetative matter 10-15 days back. On examination, there is an ulcerative lesion in the cornea, whose base has raised soft creamy infiltrate. Ulcer margin is feathery and hyphate. There are a few satellite lesions also. The most probable etiological agent is:
A. Staphylococcus aureus
B. Streptococcus pneumoniae
C. Pseudomonas aeruginosa
D. Aspergillus fumigatus
**Correct Answer:** C. Pseudomonas aeruginosa
**Core Concept:**
The presented case describes a corneal ulcer with specific clinical features like feathery and hyphae-like ulcer margin, satellite lesions, and history of trauma with vegetative matter. These features are consistent with a bacterial corneal ulcer, specifically a Gram-negative infection.
**Why the Correct Answer is Right:**
Pseudomonas aeruginosa is a Gram-negative bacterium that can cause corneal ulcers, particularly in immunocompromised patients or those with trauma history. Its clinical features include a soft, creamy infiltrate at the base of the ulcer, a feathery margin, and satellite lesions. The presence of these features in the given case suggests the involvement of Pseudomonas aeruginosa as the most probable etiological agent.
**Why Each Wrong Option is Incorrect:**
A. Staphylococcus aureus (Option A) is a common cause of bacterial corneal ulcers, but it typically presents with a dry, necrotic ulcer base and a well-defined, irregular margin.
B. Streptococcus pneumoniae (Option B) is more likely to cause a polypoidal, necrotic ulcer base, and a well-defined, irregular margin.
D. Aspergillus fumigatus (Option D) is an etiological agent for fungal corneal ulcers, often presenting with a necrotic base and well-defined, irregular margin. However, in this case, the clinical features align more closely with a bacterial infection like Pseudomonas aeruginosa.
**Clinical Pearl:**
Corneal ulcers caused by Pseudomonas aeruginosa should be suspected in patients with a history of trauma or immunocompromised status, as seen in this case. Prompt antibiotic therapy targeting Pseudomonas aeruginosa, along with appropriate antifungal therapy in case of coexisting fungal infection, should be initiated based on the clinical suspicion.
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