VB
Vikas Bhardwaj
Medical Technologist, AIIMS New Delhi
Updated: Apr 17, 2026
**Core Concept**
The presentation of inguinal swelling with enlarged lymph nodes and discharging sinuses suggests a chronic infectious or inflammatory process. **Lymphogranuloma venereum (LGV)**, a sexually transmitted infection caused by **Chlamydia trachomatis**, is known to cause such symptoms.
**Why the Correct Answer is Right**
LGV is characterized by its ability to cause **suppurative lymphadenitis**, leading to the formation of **buboes** (enlarged and painful lymph nodes) in the inguinal region, which can rupture and form discharging sinuses. The infection typically starts with a small, painless lesion on the genitalia, followed by the development of lymphadenopathy.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because it doesn't typically present with discharging sinuses.
**Option B:** Incorrect as it usually presents with a painless chancre.
**Option C:** Incorrect because it doesn't typically involve the lymph nodes in this manner.
**Clinical Pearl / High-Yield Fact**
LGV is a significant cause of lymphadenopathy in sexually active individuals, and its diagnosis should be considered in patients presenting with inguinal lymphadenopathy and a history of sexually transmitted infections.
**Correct Answer:** D. Lymphogranuloma venereum.