Esophageal carcinoma is NOT predisposed by?
Correct Answer: Scleroderma
Description: Scleroderma is not a predisposing factor for carcinoma esophagus. Predisposing factors for carcinoma esophagus: For adenocarcinoma: Chronic gastric reflux (Barrett's esophagus) For squamous cell carcinoma: Alcohol Cigarette Mucosal damage from physical agents: long term ingestion of hot liquids, lye (caustic ingestion), radiation induced strictures and chronic achalasia Other ingested carcinogens: Nitrates, nitrites, nitrosamines, smoked opiates and fungal toxins in packed vegetables. Plummer-Vinson-paterson-kelly syndrome (esophageal web + glossitis + Iron deficiency) Tylosis palmaris et plantaris (congenital hyperkeratosis and pitting of palms and soles) Human papillomavirus Bulimia (repeated microtrauma due to vomiting, may contribute to the malignant transformation of the esophageal tissue) Esophageal diveicula Ref: Harrison 17/e, Page 570 ; Schwaz 9/e, Page 862 ; Sabiston 18/e, Page 1091
Category:
Surgery
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now