Which is true of trophozoites of E.histolytica -a) Has eccentric Karyosomeb) Nuclear membrane with chromatinc) Shows erythrophagocytosisd) Presence of bacteria inside cell

**Core Concept**
The trophozoite form of Entamoeba histolytica is a protozoan parasite that invades the intestinal mucosa, causing amoebiasis. The correct answer option highlights a distinctive feature of these trophozoites.

**Why the Correct Answer is Right**
Trophozoites of E. histolytica are known for their ability to ingest and digest red blood cells, a process called erythrophagocytosis. This is a key characteristic that distinguishes them from other amoeba species. The presence of erythrophagocytosis is a result of the trophozoite's ability to extend pseudopodia and engulf red blood cells, which are then digested within the cell.

**Why Each Wrong Option is Incorrect**
* **Option A:** Eccentric karyosome is a feature of the trophozoite form of Toxoplasma gondii, not E. histolytica. This is a classic example of a distractor that requires knowledge of other parasites.
* **Option B:** Nuclear membrane with chromatins is a feature of many eukaryotic cells, including some other amoeba species. However, it is not a distinctive feature of E. histolytica trophozoites.
* **Option D:** Presence of bacteria inside the cell is not a characteristic feature of E. histolytica trophozoites.

**Clinical Pearl / High-Yield Fact**
Erythrophagocytosis is a hallmark of E. histolytica infection and can be seen in stool microscopy or histological sections of intestinal biopsies. This feature is essential for diagnosing amoebiasis.

**Correct Answer: C. Shows erythrophagocytosis**