Epidural anaesthesia is initiated in Primigravida at 38 weeks gestation, with a bolus of 15mg of Bupivacaine. Within few minutes, fetal heart rate monitoring shows variable decelerations. If scalp pH reveals fetal acidosis, compared with a normal pH, the anaesthetic absorbed by fetus will be present in
Correct Answer: Higher concentration, most in ionized form
Description: Local anaesthetics, being basic drugs become more ionized at low fetal pH. Ionized molecules are thus trapped on fetal side of circulation.
Category:
Anaesthesia
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