True about Eosinophillic granuloma -a) M.C. in 20-45 years of ageb) More common in femalec) Osteolytic lesiond) Skull is commonly affectede) Lung is commonly affected.
First, I need to recall what Eosinophilic Granuloma is. It's part of the Langerhans Cell Histiocytosis (LCH) group, right? LCH includes three main entities: Eosinophilic Granuloma (EG), Hand-Schüller-Christian Disease (HSCD), and Letterer-Siwe Disease (LSD). EG is the most common and least severe form, typically affecting the bones.
Now, let's go through each option one by one.
Option a) says it's most common in 20-45 years of age. I remember that EG can occur in any age, but there are two peaks: one in children (around 2-5 years) and another in adults (20-40s). However, the question states "M.C." which I think means "most common". If the peak is in adults 20-45, then this might be true. But I need to confirm.
Option b) claims it's more common in females. I don't recall a significant gender predilection. Maybe slightly more in males? Or is there no difference? I need to check this.
Option c) mentions osteolytic lesions. Yes, EG is characterized by osteolytic lesions, especially in the skull, femur, and other bones. That's a key feature.
Option d) says the skull is commonly affected. Definitely, the skull is a common site. The "hair-on-end" appearance on X-ray is classic for EG in the skull.
Option e) states that the lung is commonly affected. EG is primarily a bone disease. Lung involvement is more common in HSCD or other forms of LCH. So this is likely incorrect.
Now, the correct answer options would be c) and d). But the options given in the question are a) to e), and the answer format is A, B, C, D. Wait, the original question lists options a) to e), but the answer choices are labeled A to D? The user provided the question with options a-e but the answer choices as A-D. Maybe the options are a-e, and the answer is a combination. However, the correct answer here is c) and d). But the user's answer format is A-D. Wait, the user's question lists options a-e with letters A-D as answer choices. Maybe there's a formatting issue. Let me check again.
The question lists options a-e, but the answer choices are A-D. That's confusing. The original question's options are a-e, and the answer is selected from A-D. So perhaps the options are listed as a-e, but the answer is a combination of correct options. For example, if the correct options are c and d, then the answer would be C and D. However, the user's correct answer is given as C. So maybe only option c is correct? Wait, the user's correct answer is listed as C. Let me check again.
Wait, the user says "Correct Answer: C. Osteolytic lesion". But according to my knowledge, EG does present with osteoly