Pulmonary eosinophilia is seen due to which of the following infection?
The options aren't provided, but common parasites that cause this include Strongyloides stercoralis, Paragonimus, and others. Wait, the correct answer given here is Paragonimus, which is a lung fluke. Paragonimus causes paragonimiasis, which can lead to pulmonary symptoms and eosinophilia.
Now, why is Paragonimus the right answer? Because the infection triggers an immune response involving eosinophils. The larvae or eggs in the lungs cause inflammation, leading to the release of eosinophils. Other parasites like Ascaris or hookworms can also cause eosinophilia, but Paragonimus is a classic example for pulmonary involvement.
The wrong options might include other parasites. For example, Strongyloides can cause hyperinfection syndrome, but maybe not as classic pulmonary eosinophilia. Hookworms cause anemia and skin issues, not primarily pulmonary. Toxoplasma is more systemic. So each wrong option's incorrectness needs to be explained briefly.
Clinical pearl: Remember that pulmonary eosinophilia is a hallmark of Paragonimus infection. Also, Paragonimus is a lung fluke transmitted through undercooked crustaceans. Diagnosis involves finding eggs in sputum or stool. Treatment is praziquantel.
**Core Concept**
Pulmonary eosinophilia is a hallmark of parasitic infections, particularly those involving helminths that migrate through the lungs or reside in pulmonary tissues. Eosinophils are recruited to combat parasitic invaders, leading to elevated levels in lung tissues and peripheral blood.
**Why the Correct Answer is Right**
*Paragonimus westermani*, a lung fluke, causes paragonimiasis. After ingestion of infective cysts (e.g., from undercooked crustaceans), larvae penetrate the intestinal wall, migrate via the peritoneal cavity to the lungs, and mature. This migration triggers a Type I hypersensitivity reaction and eosinophilic infiltration in the lungs, leading to pulmonary eosinophilia. Radiographic findings include cavitary lesions and pleural effusion.
**Why Each Wrong Option is Incorrect**
**Option A:** *Strongyloides stercoralis* causes hyperinfection syndrome with disseminated infection, not pulmonary eosinophilia.
**Option B:** *Ascaris lumbricoides* may cause Loeffler’s syndrome (transient pulmonary eosinophilia) due to larval migration, but this is typically self-limiting.
**Option C:** *Toxoplasma gondii* is an intracellular protozoan; it does not induce pulmonary eosinophilia.
**Clinical Pearl / High-Yield Fact**
Paragonimiasis is a classic cause of chronic pulmonary eosinophilia with cavitary lung lesions. Remember the "three Fs" for diagnosis: **flesh-eating crabs**, **freshwater**, and **Far East** (endemic regions). Praziquantel is the first-line treatment.