Biochemistry Enzyme deficient in Lesch-Nyhan syndrome? A Phosphoribosyl-pyrophosphate synthetase B Xanthine oxidase C Adenine phosphoribosyl Transferase D Hypoxanthine Guanine Phosphoribosyl Transferase 💡 Explanation Enzyme deficient in Lesch-Nyhan syndrome? ✓ Correct Answer: D. Hypoxanthine Guanine Phosphoribosyl Transferase