What will happen if a bacteria acquires genes coding for restriction endonuclease aEUR’
**Core Concept:**
The question is testing the understanding of genetic modification in bacteria, specifically the role of Restriction Endonucleases. Restriction enzymes are a type of enzymes that cleave DNA molecules at specific sequences (restriction sites) present in prokaryotic and eukaryotic DNA. They are essential in molecular biology techniques such as DNA sequencing, cloning, and manipulation.
**Why the Correct Answer is Right:**
When a bacteria acquires genes coding for restriction endonuclease, it becomes resistant to infection by bacteriophages (viruses that infect bacteria) that utilize these enzymes to cleave the bacterium's DNA and replicate themselves. The newly acquired restriction endonuclease digests the bacteriophage DNA, preventing it from integrating into the host bacteria's genome and replicating.
**Why Each Wrong Option is Incorrect:**
A. This option is incorrect because it suggests that the bacteria will become more resistant to antibiotics, which is not the main outcome of acquiring restriction endonuclease genes.
B. The bacteria will not become more virulent (aggressive or harmful) due to acquiring restriction endonuclease genes, as the main purpose is to protect against bacteriophage infection.
C. This answer is incorrect as the bacteria will not gain any ability to utilize host cellular components, as the focus is on protecting against bacteriophage infection.
D. The bacteria will not become more capable of utilizing host cellular components, as the main purpose is to protect against bacteriophage infection.
**Clinical Pearl / High-Yield Fact:**
The concept of horizontal gene transference, including transduction (bacteriophage-mediated gene transmission), is crucial in understanding bacterial resistance and virulence. It is essential for understanding the spread of antibiotic resistance genes and the evolution of bacterial pathogens.
**Correct Answer:** D.
When a bacteriophage infects a bacterium, it can integrate its DNA into the host bacterium's genome. If the host bacterium already carries a restriction endonuclease gene, it can cleave the bacteriophage DNA, preventing the bacteriophage from integrating into the host's genome and replicating. This increases the bacteria's resistance to bacteriophage infection, which is the main purpose of acquiring restriction endonuclease genes.