**Core Concept**
The underlying condition being described is likely **Autosomal Dominant Polycystic Kidney Disease (ADPKD)**, characterized by the development of multiple renal cysts, often leading to **hypertension** and potentially **renal failure**. This condition is inherited in an autosomal dominant pattern, explaining the family history.
**Why the Correct Answer is Right**
Given the choices are missing, we'll focus on the typical associations with ADPKD, which include **hypertension**, **renal cysts**, and an increased risk of **intracranial aneurysms**. The condition is caused by mutations in the **PKD1** or **PKD2** genes, affecting polycystin-1 and polycystin-2 proteins, which are crucial for the structure and function of renal tubular cells.
**Why Each Wrong Option is Incorrect**
**Option A:** Would be incorrect if it stated something commonly associated with ADPKD, such as hypertension or renal cysts.
**Option B:** Similarly, if it mentioned another known complication or association, it would be incorrect.
**Option C:** If this option discussed a less common but recognized aspect of ADPKD, such as liver cysts or mitral valve prolapse, it would not be the correct answer.
**Option D:** Assuming this option might discuss something not typically associated with ADPKD, its correctness would depend on the specifics of the option.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that ADPKD is a leading cause of inherited kidney disease and can lead to significant **morbidity** and **mortality** if not properly managed. Early detection and control of hypertension are crucial in slowing the progression of renal disease.
**Correct Answer:** D.
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